Metabolic syndrome

Metabolic syndrome (MetS) is not a disease, but it is the scourge of our time. MetS, also characterized as “insulin resistance syndrome”, or “syndrome X” is increasingly recognized as an important factor in obesity, type 2 diabetes, hypertension, dyslipidemia and cardiovascular diseases.

Who does it concern?

It usually concerns people who meet the above criteria and is framed by a sedentary lifestyle and a casual and usually unbalanced diet.

The exact etiology of metabolic syndrome has not yet been fully elucidated. Studies describe the strong association of metabolic syndrome with:

  1. insulin resistance,
  2. Oxidative stress,
  3. The role of white adipose (WAT) adipocytes,
  4. Chronic microinflammation,
  5. Obesity, and
  6. The gut microbiome.

The Invisible Enemies of Health: What Leads to Metabolic Syndrome?

1. Heredity and Genes: MetS is largely driven by obesity and lipid metabolism genes (50% heredity contributes). Inclusion of relevant genetic variants in polygenic scores for MetS may prove fundamental for the high-risk group to allow early targeted interventions. 

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2. Unhealthy Lifestyle: Bad eating habits such as refined carbohydrates, consumption of sweets and saturated fats, deli meats, processed and ultra-processed foods and fast food as well as lack of exercise and other unhealthy lifestyle choices are key factors. Poor sleep, for example, can dramatically affect our metabolism.

 

Learn more about the effect of sleep on health on our page

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3. Environmental Endocrine Disruptors: Exposure to per- and polyfluorinated alkyl substances (PFAS) has been linked to adverse effects on human health, including metabolic disorders such as obesity, diabetes, and non-alcoholic fatty liver disease.

For more information, see our page on dangerous levels of toxic chemicals ..

4. Energy Intake and Expenditure: The central nervous system plays a key role in controlling both energy intake and expenditure in response to peripheral cues of energy status. Imbalances in energy intake relative to expenditure can arise due to multiple etiologies (including biological, behavioral, and environmental factors) and ultimately lead to metabolic syndrome, which leads to further disruption of endocrine function

The FGA Center solution

With the latest science and specialized tests, we evaluate the genetic, physiological and environmental factors that contribute to metabolic syndrome. We analyze single nucleotide polymorphisms (SNPs) and associated genetic variants to provide you with a personalized approach to combating metabolic syndrome.

Our program includes:

  1. Personalized Metabolite Analysis: We identify metabolites associated with insulin resistance, oxidative stress, the role of white adipose (WAT) adipocytes, chronic microinflammation, obesity, the gut microbiome, the increase and inability to burn fat .
  2. Personalized Nutrition Programs: According to your specialized results, we design nutrition programs that meet your needs.
  3. Nutritional Supplements and Lifestyle: We provide advice on specific supplements and lifestyle changes to help you achieve your goals.
  4. Ongoing Support: We monitor biological challenges as they arise to ensure your long-term success.

Discover the possibilities science gives us for transformation and wellness with the help of the FGA Center.